Basic Technologies

Modern Equipment for the Fight Against Infectious Diseases

The five basic technologies form the core of LPI’s state-of-the-art and globally unique infrastructure. They will make it much easier for users to translate their ideas and research results into applications.
Prof. Dr. Jürgen Popp, LPI Spokesman

At the LPI we complement state-of-the-art technologies with new photonic methods that are not commercially available today. In the future, users from science and industry will have access to a broad spectrum of unique light-based and molecular biological methods in combination with all the necessary technologies to accelerate the translation of new methods for diagnostics and treat- ment of infectious diseases.

In the course of 2021, the devel- opment of the LPI's technological infrastructure started: The Federal Ministry of Education and Research is funding five projects designated as basic technologies with around 50 million euros. Researchers from the four partner organizations are working in cross-institutional projects to increase the Technology Readiness Level (TRL) of the basic technologies in order to prepare them for their application in the LPI.

Multidimensional, Multimodal, Intelligent Imaging Platforms

The subject matter of the project is research and development of innovative imaging platform technologies for infection-relevant application scenarios combined with new concepts for sample preparation of cells, tissues as well as organ models and organs.

Coordinated by the Leibniz IPHT

Photonic Interaction Assays for POCT / High Throughput Platforms

In the project coordinated by Leibniz IPHT, methodological and instrumental biopho- tonic platform technologies for point-of-care (POC) and high-throughput applications are researched and realized as basic technologies for LPI.

Coordinated by the Leibniz IPHT

Artificial Intelligence for Diagnostics and Therapy

Users of LPI should be able to rely on state-of-the-art analysis methods for the evaluation of diagnostic data sets when developing their own solutions. Within the framework of the project coordinated by Friedrich Schiller University Jena, methods based on artificial intelligence, machine learning and deep learning methods are being developed.

Coordinated by the Friedrich Schiller University Jena

Highly Parallel Profiling of the Host Response to Life-threatening Infections

In infections, the course of disease and reactions of the immune system, and thus a precisely fitting therapy, are very different and individual. In the project coordinated by the University Hospital Jena, light-based methods for accompanying diagnostics and monitoring of bodily functions are being researched in order to be able to quickly and precisely characterize the individual response to the pathogen, even when pressed for time in the intensive care unit.

Coordinated by the University Hospital Jena

Innovative Molecular and Biochemical Assays for Rapid Diagnostics, Drug Development and New Therapeutic Concepts

Photo: Anna Schroll

In order to be able to develop novel individualized forms of therapy in the future, scientists in the project coordinated by Leibniz-HKI are researching molecules and therapeutic microbes as well as certain proteins and antibodies, as an alternative to conventional antibiotics. Photonics-based molecular and biochemical assays are being developed for rapid diagnostics.

Coordinated by the Leibniz HKI

Scientific Coordinators

Dr. Lisa Schmölz

Scientific Coordinator of the LPI Basic Technologies at Leibniz IPHT

Email: lisa.schmoelz@leibniz-ipht.de
Phone: +49 3641 – 20 60 17

Dr. Jeanine Linz

Scientific Coordinator of the LPI Basic Technologies at Leibniz HKI

Email: jeanine.linz@leibniz-hki.de
Phone: 03641 – 53 21 110

Dr. Sophie Thamm

Scientific Coordinator of the LPI Basic Technologies at the Friedrich Schiller University

Email: sophie.thamm@uni-jena.de
Phone: +49 3641 – 94 84 21

Dr. Andrea Schweinitz

Scientific Coordinator of the LPI Basic Technologies at the University Hospital Jena

Email: andrea.schweinitz@med.uni-jena.de
Phone: +49 3641 – 93 23 320